Armour Thyroid vs. Synthroid – A Deeper Look

Armour Thyroid vs. Synthroid–what’s the difference? Armour Thyroid is a hypothyroid medication that contains natural forms of multiple thyroid hormones.

In contrast, Synthroid is a synthetic formulation of thyroxine, a key thyroid hormone, and is the most frequently prescribed medication for individuals with hypothyroidism.

Discover the differences between these hypothyroidism medications and learn how to support a healthy thyroid naturally. 

Understanding thyroid disorders

The human thyroid gland, shaped like a butterfly, is located at the front of the neck and is connected to the trachea. 

The thyroid gland synthesizes and releases thyroid hormones, which regulate several essential physiological functions, including growth, heart rate, and body temperature. 

However, their most vital role is controlling metabolic processes such as energy expenditure, the conversion of food into energy, and the regulation of cholesterol levels.

When the thyroid gland isn’t functioning properly, thyroid hormone levels can become imbalanced, leading to a downregulation of metabolic functions linked to a range of symptoms and health issues. 

Hypothyroidism is the most common thyroid disorder and is characterized by an underactive thyroid gland that results in insufficient production of thyroid hormones.

Left untreated, an underactive thyroid can significantly slow metabolic processes linked to symptoms such as extreme fatigue, hair loss, cold intolerance, weight gain, and memory problems.

In contrast, hyperthyroidism occurs when the thyroid gland is overactive and produces excessive amounts of thyroid hormones.

This condition can accelerate metabolic processes, resulting in symptoms such as weight loss, increased heart rate, anxiety, sweating, and heat intolerance.

Thyroid function is usually evaluated with blood tests that measure levels of thyroid-stimulating hormone (TSH), a pituitary hormone that stimulates and regulates the production of thyroid hormones.

A high TSH level suggests that your body isn’t producing enough thyroid hormones, indicating a potential risk for hypothyroidism. In contrast, low TSH levels are associated with an overactive thyroid gland, which is typically indicative of hyperthyroidism.

Watch the video below to learn more about Armour Thyroid vs. Synthroid.

Armour Thyroid vs. Synthroid

Armour Thyroid and Synthroid are prescription medications utilized in thyroid hormone replacement therapy to address thyroid hormone deficiencies.

Though they both are used to treat hypothyroidism, these medications work through different mechanisms to restore thyroid hormone levels and reduce symptoms of thyroid disorders. 

Let’s take a look at the difference between Armour Thyroid and Synthroid. 

Armour Thyroid

Armour Thyroid is a hypothyroid treatment derived from desiccated thyroid extract, which is an animal-based extract typically sourced from pigs. 

This medication comprises several thyroid hormones, including thyroxine (T4), triiodothyronine (T3), and calcitonin, which are essential for energy production and calcium balance. 

Taking Armour Thyroid is considered a more natural option, as it closely mimics the hormone profile produced by the human thyroid gland.

Potential benefits

For many patients, Armour Thyroid begins working quickly, often within two to three weeks. This is likely due to the drug supplying several thyroid hormones, reducing the need for the thyroid to convert or produce them.

Because Armour Thyroid delivers both T3 and T4 hormones, it has been found particularly effective in boosting energy levels and enhancing mental clarity compared to Synthroid.

A study published in the Journal of the Endocrine Society concluded, “...patients generally feel better on Armour Thyroid compared to levothyroxine [Synthroid]. Armour Thyroid is an effective medication to use for patients who remain symptomatic on levothyroxine...”

Potential downsides 

Drug interactions may occur with Armour Thyroid, especially for those taking anticoagulants, insulin, diabetes medications, cholesterol drugs, or oral contraceptives.

Synthroid

Synthroid, generically known as levothyroxine, is a synthetic form of the thyroid hormone thyroxine. It’s an FDA-approved medication and the most prescribed treatment for hypothyroidism in the last 60 years.

Unlike Armour Thyroid, Synthroid only contains T4, which the body must convert into T3, which is the active form of thyroid hormone that regulates the metabolism of most cells. 

Potential benefits

Synthroid has been found effective at restoring T4 balance and improving mental and physical activity in those with an underactive thyroid gland. 

Additionally, Synthroid is often used to treat a specific thyroid cancer known as thyrotropin-dependent well-differentiated thyroid cancer.

Potential downsides 

Compared to Thyroid Armour, it can take longer for Synthroid users to notice benefits, as the effectiveness of this medication relies on the body’s ability to convert T4 into T3. 

Patients who can’t effectively convert thyroid hormones, such as those with liver and kidney problems and individuals with mineral deficiencies, may find that Synthroid doesn’t improve their symptoms.

Additionally, Synthroid is linked to various side effects, including headaches, nausea, appetite changes, chest pain, and excessive sweating. 

If you are considering making changes to your prescription drugs, it’s crucial to consult your healthcare provider to discuss your options, potential side effects, and the best approach to managing your thyroid condition.

Natural tips for a healthy thyroid

Hormonal imbalance, poor nutrition, and frequent eating can all play a significant role in suppressing thyroid function, increasing the risk of hypothyroidism.

Making beneficial dietary and lifestyle changes can promote optimal thyroid function and support overall well-being. 

Here are four tips to support a healthy thyroid naturally.

1. Promote hormonal balance

Hormonal imbalances such as elevated estrogen, cortisol, and insulin levels, typically linked to a diet high in carbohydrates, sugar, and processed foods, can negatively impact thyroid functions. 

High estrogen has been found to prevent thyroid hormone conversion and may block cellular uptake of T3. This might explain why hypothyroidism disproportionately affects women, particularly those who are postpartum or perimenopausal.

Cortisol, the body's main stress hormone, can inhibit thyroid hormone production and disrupt the conversion of T4 to T3, and elevated insulin levels have shown similar effects.

A study published in the International Journal of Health Sciences and Research found that hypothyroidism was associated with insulin resistance, highlighting the link between hormonal imbalances and thyroid functioning. 

2. Ensure optimal nutrient intake

In addition to hormone balance, the body requires several cofactors to effectively convert T4 to T3. These include vitamins A, D, B2, B6, and B12, as well as the minerals iodine, iron, selenium, and zinc. 

The thyroid gland contains the highest concentration of selenium in the body, which explains why this mineral is the most important nutrient for thyroid hormone metabolism and conversion.

“Selenium plays a crucial role in maintaining normal thyroid physiology,” explains Dr. Berg. “However, an imbalance of selenium and iodine can exacerbate thyroid problems, and taking these minerals together is important.” 

While supplements can aid in restoring low nutrient levels, obtaining selenium and iodine from natural sources, such as Brazil nuts, meat, eggs, fish, and sea kelp, is often more beneficial.

3. Limit carbohydrate intake

Following a nutrient-dense, low-carb diet, such as Healthy Keto®, can boost the intake of key nutrients needed for optimal thyroid function. 

In addition, Healthy Keto also minimizes the intake of antinutrients, including phytic acid, which can inhibit the absorption of essential minerals necessary for thyroid health.

Healthy Keto focuses on healthy fats, organic produce, grass-fed meats, and plenty of green leafy vegetables to provide essential nutrients for optimal thyroid health. This approach also excludes soy products, which can mimic estrogen in the body and disrupt thyroid function.

4. Practice intermittent fasting

Finally, intermittent fasting, which involves time-restricted periods of eating and fasting, may also support a healthy thyroid. 

This is likely due to its ability to lower insulin levels, reduce inflammation, and mitigate oxidative stress, all of which are linked to hypothyroidism and various autoimmune disorders.

However, it's essential to focus on nutritious meals and maintain adequate caloric intake while practicing intermittent fasting to minimize the risk of nutritional deficiencies and significant caloric deficits, both of which can adversely affect thyroid function.

Key takeaways

Armour Thyroid vs. Synthroid–what’s the difference between these two thyroid medications?

Armour Thyroid is a natural option that provides several thyroid hormones, including T3, T4, and calcitonin. In contrast, Synthroid is a synthetic form of T4 that relies on the body’s ability to convert thyroxine effectively.

In addition to medication, limiting carbs and sugars, ensuring adequate nutrient intake, practicing intermittent fasting, and supporting hormonal balance are excellent strategies for promoting thyroid function naturally. 

FAQ

1. Armour Thyroid vs. Synthroid, what’s the difference?

Armour Thyroid is a hypothyroid medication derived from desiccated thyroid extract, typically sourced from pigs. It’s a more natural option for treating hypothyroidism as it comprises the three naturally occurring thyroid hormones thyroxine (T4), triiodothyronine (T3), and calcitonin.

In contrast, Synthroid is a synthetic form of T4, which the body must convert into its active form of T3.

2. What is Armour Thyroid?

Armour Thyroid is a thyroid replacement therapy derived primarily from the desiccated thyroid glands of pics. This medication provides T4 and T3 combination therapy and calcitonin, a hormone critical for regulating the body’s calcium balance.  

It works by replacing insufficient thyroid hormones in those with hypothyroidism, helping restore metabolic function, enhance energy levels, and alleviate symptoms such as fatigue and weight gain.

3. What is Synthroid?

Synthroid is synthetically manufactured thyroid hormone that mimics T4 and is the most common medication prescribed to treat hypothyroid patients. It works by normalizing circulating levels of T4 but relies on the body’s ability to convert T4 into the active thyroid hormone T3.  

4. Can I do fasting if I have a thyroid disorder?

Yes, intermittent fasting is safe for those with thyroid disorders if combined with a nutrient-dense diet. However, avoiding an extreme calorie deficit is vital, as this can further slow metabolism and negatively impact the thyroid.

5. What is the best diet for someone with a thyroid issue?

A low-carb diet, such as Healthy Keto®, focusing on organic non-starchy vegetables, grass-fed and wild-caught meats, oily fish, and organic full-fat dairy, is an excellent dietary pattern to promote thyroid function.

6. What is the most important nutrient for a thyroid problem?

Selenium is a crucial mineral that plays a vital role in thyroid function, particularly in the conversion of T4 to T3. Alongside selenium, iodine is another trace mineral critical for optimal thyroid health, and it can be sourced from seafood and sea kelp. 

Sources

1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8089975/ 

2. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4286301/